The No.22 blade is an enlarged variant of the No.10, featuring a curved cutting edge and a flat, non-sharpened back. It is utilized for making skin incisions in cardiac and thoracic surgeries and for cutting the bronchus during lung resection procedures. Larger than the No.20 and No.21, the No.22 is compatible with handles 4, 4L, 4 Graduated, and 6B